Nowadays there are several terms that are being used in the literature to describe ME/CFS. It is a complex and multifactorial disease that not only dysregulates the central nervous system, immune system and cellular energy metabolism, but also influences physical and cognitive state. Myalgic encephalomyelitis (ME) or chronic fatigue syndrome (CFS) is post-viral or post-infectious fatigue syndrome or systemic exertional intolerance disease (SEID) that affects the functioning ability of a person and reduces the energy below the level that is considered the average. Nonsteroidal anti-inflammatory drugs are the most commonly used pharmacological drug class that reduces ME/CFS symptoms.

VAS score has a tendency to decrease with age and duration of fatigue. Fatigue, myalgia, arthralgia and sleep disturbances tend to be more prevalent in the ME/CFS patients compared to the non-ME/CFS patients. Conclusions: Comorbidities tend to present with a more severe course of ME/CFS. A negative correlation was found regarding an increase in age and number of current symptoms, as well as an increase in VAS score and the duration of fatigue and age in the ME/CFS without comorbidities group. Results: The study showed that ME/CFS with comorbidities is associated with a more severe disease. Questionnaires, specialist evaluation of the patients and visual analogue scale (VAS) measurements were used to objectify the findings. Materials and methods: Total of 65 Caucasian patients from an ambulatory care setting were included in the study. Our aim is to identify the core symptoms of ME/CFS in the outpatient setting in Riga to distinguish symptoms in patients with ME/CFS and those with symptoms of fatigue and to investigate patient thoughts on the onset, symptoms, treatment and effect of ME/CFS. Background and objectives: There is still an uncertainty regarding the clinical symptomatology and the diagnostic criteria in terms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), as different diagnostic criteria exist.

Cfs diagnosis